An organophosphate poisoning case responding the late application of Pralidoxime

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Pralidoxime for organophosphate poisoning

From their randomised trial, Kirti Pawar and colleagues report in today’s Lancet on two pralidoxime-dosing schemes in 200 patients who had moderately severe self-poisoning with organophosphorus insecticide. After a 2-g loading dose over 30 min, half received a high-dose regimen of 1 g/h pralidoxime iodide for 48 h. The other half received a lower dose: 1 g/h every 4 h. After 48 h, the lower dos...

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Effectiveness of High Dose Pralidoxime for Treatment of Organophosphate Poisoning

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Effectiveness of High Dose Pralidoxime for Treatment of Organophosphate Poisoning

Background: For effective treatment of organophosphate (OP) poisoning, development of a standardized protocol with flexible dose regimen for atropine and pralidoxime is an essential step. In this study, we aimed to assess the protocol devised in our setting; Bach Mai Hospital Poison Treatment Center, for treatment of OP poisoning that included a higher dose regimen of pralidoxime (2PAM). Method...

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A Study on Two Dose Regimens of Pralidoxime in the Management of Organophosphate Poisoning

Background: The role and proper dose of pralidoxime in the treatment of Organophosphorus (OP) compounds poisoning is an unresolved issue .This study was designed to compare the regimen recommended by the World Health Organization (WHO) with the commonly used standard regimen of pralidoxime. Methods: This was a randomized open labeled prospective study on OP poisoned patients admitted to JSS Hos...

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Acute and late complications of organophosphate poisoning.

OBJECTIVE To describe the acute and late complications of organophosphate (OP) poisoning. STUDY DESIGN Case series. PLACE AND DURATION OF STUDY Medicine Department at Peoples Medical College Hospital, Nawabshah, from June 2008 to December 2009. METHODOLOGY A total of 300 patients with organophosphate poisoning admitted to the Medical ICU were included. Baseline investigations included blo...

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ژورنال

عنوان ژورنال: Pamukkale Medical Journal

سال: 2013

ISSN: 1309-9833,1308-0865

DOI: 10.5505/ptd.2013.41275